| Clinical Signs of Hypothyroidism |
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| By W. Jean Dodds, DVM |
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| Excerpted from THYROID DISEASE AND AUTOIMMUNE THYROIDITIS. |
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| Alterations in Cellular Metabolism |
| lethargy |
weight gain |
| mental dullness |
cold intolerance |
| exercise intolerance |
mood swings |
| neurologic signs |
hyperexcitability |
| polyneuropathy |
stunted growth |
| seizures |
chronic infections |
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| Neuromuscular Problems |
| weakness |
knuckling or dragging feet |
| stiffness |
muscle wasting |
| laryngeal paralysis |
megaesophagus |
| facial paralysis |
head tilt |
| "tragic" expression |
drooping eyelids |
| incontinence |
ruptured cruciate ligament |
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| Dermatologic Diseases |
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dry, scaly skin and dandruff |
chronic offensive skin odor |
coarse, dull coat |
bilaterally symmetrical hair loss |
"rat tail"; "puppy coat" |
seborrhea with greasy skin |
hyperpigmentation |
seborrhea with dry skin |
pyoderma or skin infections |
myxedema |
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| Reproductive Disorders |
infertility |
prolonged interestrus interval |
lack of libido |
absence of heat cycles |
testicular atrophy |
silent heats |
hypospermia |
pseudopregnancy |
aspermia |
weak, dying or stillborn pups |
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| Cardiac Abnormalities |
| slow heart rate (bradycardia) |
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| cardiac arrhythmias |
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| cardiomyopathy |
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| Gastrointestinal Disorders |
constipation |
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| diarrhea |
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| vomiting |
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| Hematologic Disorders |
| bleeding |
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| bone marrow failure |
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| low red blood cells (anemia), white blood cells, platelets |
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| Ocular Diseases |
corneal lipid deposits |
corneal ulceration |
uveitis |
keratoconjunctivitis sicca or "dry eye" |
infections of eyelid glands
(Meibomian gland) |
Vogt-Koyanagi-Harada syndrome |
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| Ocular Diseases |
| IgA deficiency |
loss of smell (dysosmia) |
| loss of taste |
glycosuria |
| other |
chronic active hepatitis |
| endocrinopathies |
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| Adrenal Pancreatic |
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| Parathyroid |
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